Impact of Antifungal Compounds on Viability and Anti- Aspergillus Activity of Human Natural Killer Cells-Reference-Cited by-同舟云学术

Impact of Antifungal Compounds on Viability and Anti- Aspergillus Activity of Human Natural Killer Cells

Published:2019-02 Issue:2 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Schmidt Stanislaw¹,Schubert Ralf²,Tramsen Lars¹,Lehrnbecher Thomas¹

Affiliation:

1. Division of Pediatric Hematology and Oncology, Johann Wolfgang Goethe-University, Frankfurt, Germany

2. Division of Pediatric Pulmonology, Allergology and Cystic Fibrosis, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany

Abstract

Despite the availability of new antifungal compounds, invasive aspergillosis carries high morbidity and mortality in hematopoietic stem cell transplant recipients. In vitro studies and animal models suggest that the adoptive transfer of natural killer (NK) cells might be a promising immunotherapeutic option in this setting.

Funder

Gilead Sciences

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01993-18

Reference31 articles.

1. Prospective Surveillance for Invasive Fungal Infections in Hematopoietic Stem Cell Transplant Recipients, 2001–2006: Overview of the Transplant‐Associated Infection Surveillance Network (TRANSNET) Database

2. Population-Based Analysis of Invasive Fungal Infections, France, 2001–2010

3. Immunotherapy in Invasive Fungal Infection - Focus on Invasive Aspergillosis