A Systematic Review and Meta-analysis of the Prevalence of Community-Onset Bloodstream Infections among Hospitalized Patients in Africa and Asia

Author:

Marchello Christian S.1ORCID,Dale Ariella P.2,Pisharody Sruti3,Rubach Matthew P.4,Crump John A.1

Affiliation:

1. Centre for International Health, University of Otago, Dunedin, New Zealand

2. Colorado Department of Public Health and Environment, Denver, Colorado, USA

3. Duke University School of Medicine, Durham, North Carolina, USA

4. Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA

Abstract

Community-onset bloodstream infections (CO-BSI) are major causes of severe febrile illness and death worldwide. In light of new data and the growing problem of antimicrobial resistance (AMR) among pathogens causing BSI, we undertook a systematic review of hospital-based studies of CO-BSI among patients hospitalized with fever.

Funder

HHS | National Institutes of Health

Manatu Hauora | Health Research Council of New Zealand

Bill and Melinda Gates Foundation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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4. Centers for Disease Control and Prevention. 2019. National Hospital Ambulatory Medical Care Survey: 2015 emergency department summary tables. https://www.cdc.gov/nchs/data/nhamcs/web_tables/2015_ed_web_tables.pdf.

5. A novel electronic algorithm using host biomarker point-of-care tests for the management of febrile illnesses in Tanzanian children (e-POCT): A randomized, controlled non-inferiority trial

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