Engineered Biosynthesis of a Novel Amidated Polyketide, Using the Malonamyl-Specific Initiation Module from the Oxytetracycline Polyketide Synthase
Author:
Affiliation:
1. Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, California 90095
2. Department of Molecular Biology and Biochemistry, University of California, Irvine, California 92697
Abstract
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Link
https://journals.asm.org/doi/pdf/10.1128/AEM.72.4.2573-2580.2006
Reference66 articles.
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2. Cloning and heterologous expression in Streptomyces lividans of Streptomyces rimosus genes involved in oxytetracycline biosynthesis
3. Boehlein, S. K., N. G. Richards, and S. M. Schuster. 1994. Glutamine-dependent nitrogen transfer in Escherichia coli asparagine synthetase B. Searching for the catalytic triad. J. Biol. Chem.269:7450-7457.
4. Boehlein, S. K., S. M. Schuster, and N. G. Richards. 1996. Glutamic acid gamma-monohydroxamate and hydroxylamine are alternate substrates for Escherichia coli asparagine synthetase B. Biochemistry35:3031-3037.
5. Boehlein, S. K., J. D. Stewart, E. S. Walworth, R. Thirumoorthy, N. G. Richards, and S. M. Schuster. 1998. Kinetic mechanism of Escherichia coli asparagine synthetase B. Biochemistry37:13230-13238.
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