Yersinia pseudotuberculosis Exploits CD209 Receptors for Promoting Host Dissemination and Infection

Author:

He Ying-Xia1,Ye Cheng-Lin1,Zhang Pei1,Li Qiao1,Park Chae Gyu2,Yang Kun3,Jiang Ling-Yu1,Lv Yin1,Ying Xiao-Ling1,Ding Hong-Hui1,Huang Hong-Ping1,Mambwe Tembo John14,Li An-Yi1,Cheng Bing1,Zhang Shu-Sheng5,Zheng Guo-Xing5,Chen Shi-Yun6,Li Wei7ORCID,Xia Lian-Xu7,Kan Biao7,Wang Xin7,Jing Huai-Qi7,Yang Rui-Fu8,Peng Hua9,Fu Yang-Xin10,Klena John D.11,Skurnik Mikael12ORCID,Chen Tie1

Affiliation:

1. Department of Clinical Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Sciences and Technology, Wuhan, Hubei, China

2. Laboratory of Immunology, Brain Korea 21 PLUS Project for Medical Science, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea

3. Department of Pathogen Biology and Immunology, Shihezi University School of Medicine, Shihezi, Xinjiang, China

4. Department of Paediatrics & Child Health, The University of Zambia–University College London Medical School at Zambia, Lusaka, Zambia

5. Department of Biomedical Science, College of Medicine-Rockford, University of Illinois at Chicago, Rockford, Illinois, USA

6. Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China

7. Department of Diarrheal Diseases, National Institute for Communicable Diseases Control and Prevention, Beijing, China

8. State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

9. Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

10. Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA

11. Centers for Disease Control and Prevention, Atlanta, Georgia, USA

12. Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland

Abstract

Yersinia pseudotuberculosis is a Gram-negative enteropathogen and causes gastrointestinal infections. It disseminates from gut to mesenteric lymph nodes (MLNs), spleen, and liver of infected humans and animals.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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