Affiliation:
1. Department of Laboratory Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
Abstract
The QuantiFERON-TB Gold plus (QFT-Plus) assay, an interferon gamma (IFN-γ) release assay (IGRA), was recently introduced as the next version of the QuantiFERON-TB Gold In-Tube (QFT-GIT) assay for diagnosing latent tuberculosis (TB). Whereas the QFT-GIT assay uses only one TB tube that induces a cell-mediated immune (CMI) response of CD4
+
T cells, the QFT-Plus has an additional TB antigen 2 tube (TB2) for the CMI response of CD8
+
T and CD4
+
T cells, in addition to a TB antigen 1 (TB1) tube for the CMI response of CD4
+
T cells only.
Publisher
American Society for Microbiology
Cited by
18 articles.
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