Affiliation:
1. Department of Microbiology and Immunology, University of Western Ontario, London, Ontario, Canada
Abstract
The branched-chain amino acids (BCAAs [Ile, Leu, and Val]) represent important nutrients in bacterial physiology, with roles that range from supporting protein synthesis to signaling and fine-tuning the adaptation to amino acid starvation. In some pathogenic bacteria, the adaptation to amino acid starvation includes induction of virulence gene expression: thus, BCAAs support not only proliferation during infection, but also the evasion of host defenses.
Funder
Cystic Fibrosis Canada
Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada
Gouvernement du Canada | Canadian Institutes of Health Research
Publisher
American Society for Microbiology
Cited by
90 articles.
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