Clostridium perfringens Produces an Adhesive Pilus Required for the Pathogenesis of Necrotic Enteritis in Poultry-Reference-Cited by-同舟云学术

Clostridium perfringens Produces an Adhesive Pilus Required for the Pathogenesis of Necrotic Enteritis in Poultry

Published:2021-03-08 Issue:7 Volume:203 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Lepp D.¹,Zhou Y.¹²,Ojha S.³,Mehdizadeh Gohari I.³,Carere J.¹,Yang C.²,Prescott J. F.³,Gong J.¹^ORCID

Affiliation:

1. Guelph Research and Development Centre, Agriculture and Agri-Food Canada, Guelph, Ontario, Canada

2. Department of Animal Science, University of Manitoba, Winnipeg, Manitoba, Canada

3. Department of Pathobiology, University of Guelph, Guelph, Ontario, Canada

Abstract

In necrotic enteritis (NE), an intestinal disease of chickens, Clostridium perfringens cells adhere tightly to damaged intestinal tissue, but the factors involved are not known. We previously discovered a cluster of C. perfringens genes predicted to encode a pilus, a hair-like bacterial surface structure commonly involved in adherence.

Funder

Gouvernement du Canada | Agriculture and Agri-Food Canada

Canadian Poultry Research Council

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.00578-20

Reference51 articles.

1. An update on the human and animal enteric pathogen Clostridium perfringens

2. Expansion of the Clostridium perfringens toxin-based typing scheme