Reappraising the Value of HIV-1 Vaccine Correlates of Protection Analyses

Author:

Klasse P. J.1ORCID,Moore John P.1ORCID

Affiliation:

1. Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, USA

Abstract

With the much-debated exception of the modestly reduced acquisition reported for the RV144 efficacy trial, HIV-1 vaccines have not protected humans against infection, and a vaccine of similar design to that tested in RV144 was not protective in a later trial, HVTN 702.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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