Affiliation:
1. Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon 97331
Abstract
The production of glutamic γ-semialdehyde, an intermediate in the synthesis of proline, was inhibited in
Escherichia coli
by physiological concentrations of penicillin. Sucrose (0.6
m
) and sodium chloride (0.1
m
) prevented penicillin inhibition of glutamic γ-semialdehyde synthesis. Cells which were in the stationary phase, or which had been permitted to metabolize without growth, were insensitive to the effects of penicillin on glutamic γ-semialdehyde synthesis.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
5 articles.
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