Aminoglycoside Antibiotics: Inactivation by Phosphorylation in Escherichia coli Carrying R Factors-Reference-Cited by-同舟云学术

Aminoglycoside Antibiotics: Inactivation by Phosphorylation in Escherichia coli Carrying R Factors

Published:1969-11 Issue:2 Volume:100 Page:1144-1146
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Ozanne B.¹,Benveniste R.¹,Tipper D.¹,Davies J.¹

Affiliation:

1. Department of Biochemistry and Department of Pharmacology, University of Wisconsin, Madison, Wisconsin 53706

Abstract

R-factor strains which are streptomycin-resistant and spectinomycin-sensitive have been found to inactivate streptomycin by a new mechanism. The 3′-OH group of the 2-deoxy-2-methylamino- l -glucopyranosyl moiety is phosphorylated.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.100.2.1144-1146.1969

Reference11 articles.

1. Resistance factormediated streptomycin resistance;Harwood J. H.;J. Bacteriol.,1969

2. Isolation of kanamycin and paromamine inactivated by E. coil carrying R-factors;Kondo S.;J. Antibiot. (Tokyo) Ser. A,1968

3. The release of enzymes by osmotic shock from Escherichia coll in exponential phase;Nossal H. C.;J. Biol. Chem.,1966

4. Chloramphenicol, dihydrostreptomycin, and kanamycin-inactivating enzymes from multiple drug resistant Escherichia colt carrying episome R;Okamoto S.;Nature,1965

5. Studies on inactivation of kanamycin and resistances of E. coil;Okanishi M.;J. Antibiot. (Tokyo) Ser. A,1967

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