Molecular Determinants of Human Rhinovirus Infection, Assembly, and Conformational Stability at Capsid Protein Interfaces
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Published:2022-12-14
Issue:23
Volume:96
Page:
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ISSN:0022-538X
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Container-title:Journal of Virology
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language:en
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Short-container-title:J Virol
Author:
Valiente Luis1,
López-Argüello Silvia1,
Rodríguez-Huete Alicia1,
Valbuena Alejandro1ORCID,
Mateu Mauricio G.1ORCID
Affiliation:
1. Centro de Biología Molecular “Severo Ochoa” (CSIC-UAM), Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spain
Abstract
The rising concern about the serious medical and socioeconomic consequences of respiratory infections by HRV has elicited a renewed interest in the development of anti-HRV drugs. The conversion into effective drugs of compounds identified via screening, as well as antiviral drug design, rely on the acquisition of fundamental knowledge about the targeted viral elements and their roles during specific steps of the infectious cycle.
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
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