Typing of Neisseria gonorrhoeae Isolates in Shenzhen, China, from 2014 to 2018 Reveals the Shift of Genotypes Significantly Associated with Antimicrobial Resistance-Reference-Cited by-同舟云学术

Typing of Neisseria gonorrhoeae Isolates in Shenzhen, China, from 2014 to 2018 Reveals the Shift of Genotypes Significantly Associated with Antimicrobial Resistance

Published:2021-04-19 Issue:5 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Li Yizhun¹,Li Yamei²³,Xiu Leshan²³,Zeng Yaling¹,Zhang Chi²³,Sun Liying²³,Zhang LuLu²³,Wang Feng¹,Peng Junping²³^ORCID

Affiliation:

1. Shenzhen Center for Chronic Disease Control, Shenzhen, People’s Republic of China

2. NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China

3. Key Laboratory of Respiratory Disease Pathogenomics, Chinese Academy of Medical Sciences, Beijing, People’s Republic of China

Abstract

The growing antimicrobial resistance (AMR) in Neisseria gonorrhoeae is a serious global threat to gonococcal therapy. Molecular typing is an ideal tool to reveal the association between specific genotypes and resistance phenotypes that provide effective data for tracking the transmission of resistant clones of N. gonorrhoeae . In our study, we aimed to describe the molecular epidemiology of AMR and the distribution of resistance-associated genotypes in Shenzhen, China, during 2014 to 2018.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02311-20

Reference52 articles.

1. Susceptibility of Neisseria gonorrhoeae to azithromycin and ceftriaxone in China: A retrospective study of national surveillance data from 2013 to 2016

2. WHO. 2018. Report on global sexually transmitted infection surveillance. WHO, Geneva, Switzerland.

3. Emergence and Spread of Cephalosporin-Resistant Neisseria gonorrhoeae with Mosaic penA Alleles, South Korea, 2012–2017

4. WHO. 2016. WHO guidelines for the treatment of Neisseria gonorrhoeae. WHO, Geneva, Switzerland.

5. Update to CDC's Treatment Guidelines for Gonococcal Infection, 2020

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Neisseria gonorrhoeae ST-1901 in Rio de Janeiro from 2006 to 2022: Phylogeny and antimicrobial resistance evolution of a well-succeeded pathogen;International Journal of Antimicrobial Agents;2024-10

2. High-level ceftriaxone resistance due to transfer of penA allele 60.001 into endemic gonococcal lineages in Hangzhou, China;Journal of Antimicrobial Chemotherapy;2024-08-26

3. Emergence of Neisseria gonorrhoeae Clone with Reduced Susceptibility to Sitafloxacin in China: An In Vitro and Genomic Study;Antibiotics;2024-05-20

4. Antimicrobial resistance and heterogeneity of Neisseria gonorrhoeae isolated from patients attending sexually transmitted infection clinics in Lusaka, Zambia;BMC Genomics;2024-03-18

5. Genomic epidemiology of Neisseria gonorrhoeae in Shenzhen, China, during 2019–2020: increased spread of ceftriaxone-resistant isolates brings insights for strengthening public health responses;Microbiology Spectrum;2023-10-17