Methamphetamine Impairs IgG1-Mediated Phagocytosis and Killing of Cryptococcus neoformans by J774.16 Macrophage- and NR-9640 Microglia-Like Cells

Author:

Aslanyan Lilit1,Lee Hiu H.1,Ekhar Vaibhav V.2,Ramos Raddy L.1,Martinez Luis R.123

Affiliation:

1. Department of Biomedical Sciences, NYIT College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, New York, USA

2. Department of Biomedical Sciences, Long Island University Post, Brookville, New York, USA

3. Department of Biological Sciences, The Border Biomedical Research Center, The University of Texas at El Paso, El Paso, Texas, USA

Abstract

The prevalence of methamphetamine (METH) use is estimated at ∼35 million people worldwide, with over 10 million users in the United States. Chronic METH abuse and dependence predispose the users to participate in risky behaviors that may result in the acquisition of HIV and AIDS-related infections.

Funder

HHS | NIH | National Institute of General Medical Sciences

HHS | NIH | National Institute on Minority Health and Health Disparities

American Association for the Advancement of Science

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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