Antifungal Susceptibility Testing Identifies the Abdominal Cavity as a Source of Candida glabrata-Resistant Isolates-Reference-Cited by-同舟云学术

Antifungal Susceptibility Testing Identifies the Abdominal Cavity as a Source of Candida glabrata-Resistant Isolates

Published:2021-11-17 Issue:12 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Díaz-García Judith¹²^ORCID,Mesquida Aina¹²^ORCID,Gómez Ana¹²^ORCID,Machado Marina¹²^ORCID,Martín-Rabadán Pablo¹²,Alcalá Luis¹²,Sánchez-Carrillo Carlos¹²³,Reigadas Elena¹²^ORCID,Vicente Teresa¹²,Muñoz Patricia¹²³⁴^ORCID,Escribano Pilar¹²^ORCID,Guinea Jesús¹²³^ORCID

Affiliation:

1. Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Madrid, Spain

2. Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain

3. CIBER Enfermedades Respiratorias-CIBERES (CB06/06/0058), Madrid, Spain

4. Medicine Department, Faculty of Medicine, Universidad Complutense de Madrid, Madrid, Spain

Abstract

To identify unrecognized niches of resistant Candida isolates and compartmentalization, we retrospectively studied the antifungal susceptibility of 1,103 Candida spp. isolates from blood cultures, nonblood sterile samples, and nonsterile samples. Antifungal susceptibility was assessed by EUCAST E.Def 7.3.2; sequencing and genotyping of the FKS1-2 and ERG11 genes were carried out for non-wild-type isolates.

Funder

Fondo de Investigación Sanitaria

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01249-21

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