Affiliation:
1. Laboratory of Bacterial Pathogenesis, The Rockefeller University, New York, New York
Abstract
ABSTRACT
Pal and Cpl-1, two purified bacteriophage lytic enzymes, were tested for their in vitro activity, alone and in combination, against several serotypes of
Streptococcus pneumoniae
, including penicillin-resistant strains. The enzymes demonstrated synergism in their ability to cleave the bacterial peptidoglycan and thus may be more efficient for the prevention and elimination of pneumococcal colonization.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
129 articles.
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