Enzymatic Action on the Capsular Material Produced by Pseudomonas aeruginosa of Cystic Fibrosis Origin

Author:

Doggett Robert G.1,Harrison Gunyon M.1,Stillwell Richard N.1,Wallis Everett S.1

Affiliation:

1. Bacteriology Department, Texas Institute for Rehabilitation and Research, and Department of Pediatrics, Department of Rehabilitation, and Department of Biochemistry, Baylor University College of Medicine, Houston, Texas

Abstract

Doggett, Robert G. (Texas Institute for Rehabilitation and Research, Houston), Gunyon M. Harrison, Richard N. Stillwell, and Everett S. Wallis . Enzymatic action on the capsular material produced by Pseudomonas aeruginosa of cystic fibrosis origin. J. Bacteriol. 89: 476–480. 1965.—An enzymatic study of the action of α- and β-amylases on the slime envelope produced by Pseudomonas aeruginosa originating from patients with cystic fibrosis (CF) has been reported. It has been shown that these two enzymes in combination prevent the formation of the abnormal ethanol-benzene insoluble mucoid present in the slime layer of the above organism of CF origin. Evidence is also given which suggests that this organism can serve as a tool for studies of chemical abnormalities in the mucous metabolism of CF individuals.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference7 articles.

1. A preliminary report on the comparison of some properties of Pseudomonas aeruginosa isolated from cystic figrosis patients and non-cystic fibrosis patients infected with the organism;DOGGETT Bi.;Texas Rep. Biol. Med.,1962

2. Comparison of some properties of Pseudomonas aeruginosa from infections in persons with and without cystic fibrosis;DOGGETT R. G.;J. Bacteriol.,1964

3. The flora of the respiratory tract of patients with CF of the pancreas;HUANG N., E.;J. Pediat.,1961

4. Respiratory tract bacteriology in cystic fibrosis;IACOCCA V. F.;Am. J. Diseases Children.,1963

5. Two simple media for the demonstration of pyocyanin and fluorescein;KING E. O.;J. Lab. Clin. Med.,1954

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