Comparison of the Panther Fusion and BD MAX Group B Streptococcus (GBS) Assays for Detection of GBS in Prenatal Screening Specimens

Author:

Berry Gregory J.12,Zhang Fan1,Manji Ryhana1,Juretschko Stefan12

Affiliation:

1. Infectious Disease Diagnostics, Northwell Health Laboratories, Little Neck, New York, USA

2. Department of Pathology and Laboratory Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, East Garden City, New York, USA

Abstract

Streptococcus agalactiae or group B Streptococcus (GBS) is the cause of early- and late-onset GBS disease in neonates and can present as septicemia, meningitis, and pneumonia. Our objective was to compare the performance of two FDA-approved nucleic acid amplification tests (NAATs), the Panther Fusion and BD MAX systems, for detection of GBS in vaginal-rectal screening specimens. A total of 510 vaginal-rectal prepartum specimens were tested simultaneously in both NAATs following broth enrichment.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference9 articles.

1. The American College of Obstetricians and Gynecologists

2. Centers for Disease Control and Prevention. 2016. Active bacterial core surveillance (ABCs) report: emerging infections program network–group B Streptococcus 2016. Centers for Disease Control and Prevention Atlanta GA.

3. Edwards MS, Baker CJ. 2005. Group B streptococcal infections, p 1091–1156. In Remington JS, Klein JO (ed), Infectious diseases of the fetus and newborn infant, 5th ed. Saunders, Philadelphia, PA.

4. Prevention of perinatal group B streptococcal disease: revised guidelines from CDC;Verani JR;MMWR Recomm Rep,2010

5. A history of neonatal group B streptococcus with its related morbidity and mortality rates in the United States

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