gp96-Peptide Vaccination of Mice against Intracellular Bacteria-Reference-Cited by-同舟云学术

gp96-Peptide Vaccination of Mice against Intracellular Bacteria

Published:2001-06 Issue:6 Volume:69 Page:4164-4167
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Zügel Ulrich¹,Sponaas Anne-Marit²,Neckermann Jutta¹,Schoel Bernd¹,Kaufmann Stefan H. E.¹²

Affiliation:

1. Department of Immunology, University of Ulm, 89070 Ulm,1 and

2. Max Planck Institute for Infection Biology, 10117 Berlin,2 Germany

Abstract

ABSTRACT This work demonstrates that gp96 preparations isolated from cells infected with intracellular bacteria induce cytotoxic T-lymphocyte responses and confer protection. Our findings extend previous reports on the immunogenicity of gp96-associated peptides to antigens derived from intracellular bacteria. Immunization with gp96 may therefore represent a promising vaccination strategy against bacterial pathogens.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.69.6.4164-4167.2001

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