Mutagenesis by Mutator Gene mutH1 in Continuous Cultures of Escherichia coli-Reference-Cited by-同舟云学术

Mutagenesis by Mutator Gene mutH1 in Continuous Cultures of Escherichia coli

Published:1974-07 Issue:1 Volume:119 Page:33-35
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Nestmann Earle R.¹,Hill Ruth F.¹

Affiliation:

1. Department of Biology, York University, Downsview, Ontario, M3J 1P3 Canada

Abstract

Mutability as a function of growth rate was examined in bacterial strains containing mutator gene mutH1 . The rate of mutation to bacteriophage T5 resistance was found to be proportional to rate of growth in glucose-limited chemostat cultures. This finding supports the hypothesis that the mutator mutH1 gene product increases the error frequency during deoxyribonucleic acid replication.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.119.1.33-35.1974

Reference23 articles.

1. Selective mechanisms of bacteria;Atwood K.;Cold Spring Harbor Symp. Quant. Biol.,1951

2. Drake J. W.1970. The molecular basis of mutation. Holden-Day San Francisco.

3. Induction of mutation in chloramphenicol-inhibited bacteria;Glass E. A.;J. Bacteriol.,1959

4. Ultraviolet-induced lethality and reversion to prototrophy in Escherichia coli strains with normal and reduced dark repair ability;Hill R. F.;Photochem. Photobiol.,1965

5. Do dark repair mechanisms for UVinduced primary damage affect spontaneous mutation;Hill R. F.;Mutat. Res.,1968

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