Substitution of S179P in the Lyssavirus Phosphoprotein Impairs Its Interferon Antagonistic Function-Reference-Cited by-同舟云学术

Substitution of S179P in the Lyssavirus Phosphoprotein Impairs Its Interferon Antagonistic Function

Published:2022-11-23 Issue:22 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Wang Zongmei¹²,Yuan Yueming¹²,Zhang Yuan¹²,Zhang Chengguang¹²,Sui Baokun¹²,Zhao Jianqing¹²,Zhou Ming¹²,Chen Huanchun¹²,Fu Zhen F.¹²,Zhao Ling¹²^ORCID

Affiliation:

1. State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China

2. Key Laboratory of Preventive Veterinary Medicine of Hubei Province, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China

Abstract

Interferon (IFN) and the IFN-induced cellular antiviral response constitute the first line of defense against viral invasion. Evading host innate immunity, especially IFN signaling, is the key step required for lyssaviruses to establish infection.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01125-22

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