Predominant CD4 T-lymphocyte tropism of human herpesvirus 6-related virus-Reference-Cited by-同舟云学术

Predominant CD4 T-lymphocyte tropism of human herpesvirus 6-related virus

Published:1989-07 Issue:7 Volume:63 Page:3161-3163
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Takahashi K¹,Sonoda S¹,Higashi K¹,Kondo T¹,Takahashi H¹,Takahashi M¹,Yamanishi K¹

Affiliation:

1. Department of Virology, Research Institute for Microbial Diseases, Osaka University, Japan.

Abstract

Human herpesvirus 6 (HHV-6)-related virus was isolated from CD4+ CD8- and CD3+ CD4+ mature T lymphocytes but could not be isolated from CD4- CD8+, CD4- CD8-, and CD3- T cells in the peripheral blood of exanthem subitum patients. HHV-6-related virus predominantly infected CD4+ CD8+, CD4+ CD8-, and CD3+ CD4+ cells with mature phenotypes and rarely infected CD4- CD8+ cells from cord blood mononuclear cells, which suggested predominant CD4 mature T-lymphocyte tropism of HHV-6-related virus.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.63.7.3161-3163.1989

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