Identification of LytSR-regulated genes from Staphylococcus aureus

Author:

Brunskill E W1,Bayles K W1

Affiliation:

1. Program in Molecular and Cell Biology, University of Maryland, Baltimore County 21228, USA.

Abstract

In this report, the characterization of a Staphylococcus aureus operon containing two LytSR-regulated genes, lrgA and lrgB, is described. Sequence and mutagenesis studies of these genes suggest that lrgA encodes a murein hydrolase exporter similar to bacteriophage holin proteins while lrgB may encode a protein having murein hydrolase activity.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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