Affiliation:
1. Department of Microbiology, University of Cape Town, Rondebosch 7700, South Africa
Abstract
The morphological and cytological changes which occurred in
Clostridium acetobutylicum
P262 during the production of acetone, butanol, and ethanol in an industrial fermentation medium were identified and correlated with the growth and physiological changes. The swollen, cigar-shaped clostridial forms were involved in the conversion of acids to neutral solvents, and there was a correlation between the number of clostridial forms and the production of solvents. Sporulation mutants which were unable to form clostridial stages (
cls
mutants) did not produce solvents. Oligosporogenous mutants which showed reduced clostridial stage formation produced intermediate levels of solvents. Sporulation mutants blocked after the clostridial stage, which were unable to form mature spores (
spo
mutants), produced normal levels of solvents.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Reference22 articles.
1. Autolytic activity and an autolysis-deficient mutant of Clostridium acetobutylicum;Allcock E. R.;Appl. Environ. Microbiol.,1981
2. Bacteriocin production by Clostridium acetobutylicum in an industrial fermentation process;Barber J. M.;Appl. Environ. Microbiol.,1979
3. Studies on the acetone-butyl alcohol fermentation. I. Nutritional and other factors involved in the preparation of active suspensions of Clostridium acetobutylicum (Weizmann);Davies R.;Biochem. J.,1941
4. Bacillus subtilis mutants altered in spore morphology and RNA polymerase activity;Doi R. H.;Proc. Natl. Acad. Sci. U.S.A.,1970
5. Fitz-James P. and E. Young. 1969. Morphology of sporulation p. 39-72. In G. W. Gould and A. Hurst (ed.) The bacterial spore. Academic Press Inc. London.
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