Affiliation:
1. Microbiology & Immunology, Gifu Pharmaceutical University, Gifu, Japan
Abstract
Although GPCMV provides a useful animal model for studies on the pathogenesis of congenital CMV infection and the development of CMV vaccine strategies, our understanding of the viral mechanisms by which it evades apoptosis of infected cells has been limited in comparison with those of murine and human CMVs. Here, we report a second GPCMV apoptosis inhibitor (42 amino acids in length) that interacts with BAK, a Bcl-2 family proapoptotic protein.
Funder
MEXT | Japan Society for the Promotion of Science
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology