FgHtf1 Regulates Global Gene Expression towards Aerial Mycelium and Conidiophore Formation in the Cereal Fungal Pathogen Fusarium graminearum

Author:

Fan Gaili12,Zheng Huawei3,Zhang Kai45,Devi Ganeshan Veena6,Opiyo Stephen Obol78,Liu Dan1,Li Mingyang1,Li Guangpu9,Mitchell Thomas K.6,Yun Yingzi1,Wang Zonghua13ORCID,Lu Guo-dong1

Affiliation:

1. State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Fujian Agriculture and Forestry University, Fuzhou, China

2. Xiamen Greening Administration Center, Xiamen, China

3. Institute of Oceanography, Minjiang University, Fuzhou, China

4. State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China

5. Department of Plant Pathology, Key Laboratory of Plant Pathology, Ministry of Agriculture, China Agricultural University, Beijing, China

6. Department of Plant Pathology, The Ohio State University, Columbus, Ohio, USA

7. Molecular and Cellular Imaging Center, Columbus, Ohio, USA

8. Ohio Agriculture Research Development Center, The Ohio State University, Columbus, Ohio, USA

9. Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA

Abstract

The homeobox gene family of transcription factors is known to be involved in the development and conidiation of filamentous fungi. However, the regulatory mechanisms and downstream targets of homeobox genes remain unclear. FgHtf1 is a homeobox transcription factor that is required for phialide development and conidiogenesis in the plant pathogen F. graminearum . In this study, we identified FgHtf1-controlled target genes and binding motifs. We found that, besides autoregulation, FgHtf1 also controls global gene expression and promotes conidiation in F. graminearum by activation of genes necessary for aerial growth, FgCON7 , and other conidiation-related genes.

Funder

China Scholarship Council

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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