Characterization of SXT/R391 Integrative and Conjugative Elements in Proteus mirabilis Isolates from Food-Producing Animals in China-Reference-Cited by-同舟云学术

Characterization of SXT/R391 Integrative and Conjugative Elements in Proteus mirabilis Isolates from Food-Producing Animals in China

Published:2016-03 Issue:3 Volume:60 Page:1935-1938
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Lei Chang-Wei¹²³⁴,Zhang An-Yun¹²³⁴,Wang Hong-Ning¹²³⁴,Liu Bi-Hui¹²³⁴,Yang Li-Qin¹³,Yang Yong-Qiang¹²³⁴

Affiliation:

1. College of Life Science, Sichuan University, Chengdu, People's Republic of China

2. Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, Chengdu, People's Republic of China

3. Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, People's Republic of China

4. 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, People's Republic of China

Abstract

ABSTRACT SXT/R391 integrative and conjugative elements (ICEs) were detected in 8 out of 125 Proteus mirabilis isolates from food-producing animals in China. Whole-genome sequencing revealed that seven ICEs were identical to ICE Pmi Jpn1, carrying the cephalosporinase gene bla CMY-2 . Another one, designated ICE Pmi Chn1, carried five resistance genes. All eight ICEs could be transferred to Escherichia coli via conjugation. The results highlight the idea that animal farms are important reservoir of the SXT/R391 ICE-containing P. mirabilis .

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02852-15

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