Cloning of the gene, speB, for streptococcal pyrogenic exotoxin type B in Escherichia coli-Reference-Cited by-同舟云学术

Cloning of the gene, speB, for streptococcal pyrogenic exotoxin type B in Escherichia coli

Published:1988-06 Issue:6 Volume:56 Page:1665-1667
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Bohach G A¹,Hauser A R¹,Schlievert P M¹

Affiliation:

1. Department of Microbiology, Medical School, University of Minnesota, Minneapolis 55455.

Abstract

The structural gene encoding streptococcal pyrogenic exotoxin type B, designated speB, was cloned in Escherichia coli and localized onto a 4.5-kilobase BamHI-BglII DNA fragment. Streptococcal pyrogenic exotoxin type B, partially purified from E. coli clones, was immunologically related to streptococcus-derived toxin. Also, toxin derived from either E. coli or Streptococcus pyogenes had similar lymphocyte mitogenic activity and molecular weight (29,300) and displayed comparable microheterogeneity when evaluated by isoelectric focusing.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.56.6.1665-1667.1988

Reference31 articles.

1. Heterogeneity of group A streptococcal pyrogenic exotoxin type B;Barsumian E. L.;Infect. Immun.,1978

2. The staphylococcal enterotoxins: similarities;Bergdoll M. S.;Contrib. Microbiol. Immunol.,1973

3. Bergdoll M. S. and P. M. Schlievert. 1984. Toxic shock syndrome toxin. Lancet ii:691.

4. Studies on Iysogenesis. I. The mode of phage liberation by Iysogenic Escherichia coli;Bertani G.;J. Bacteriol.,1951

5. Staphylococcal enterotoxin A is encoded by phage;Betley M. J.;Science,1985

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