Dose-Dependent Response to Infection with Ebola Virus in the Ferret Model and Evidence of Viral Evolution in the Eye-Reference-Cited by-同舟云学术

Dose-Dependent Response to Infection with Ebola Virus in the Ferret Model and Evidence of Viral Evolution in the Eye

Published:2021-11-23 Issue:24 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Watson Robert J.¹^ORCID,Tree Julia¹,Fotheringham Susan A.¹,Hall Yper¹,Dong Xiaofeng²,Steeds Kimberley¹,Gouriet Jade¹,Salguero Francisco J.¹,Burton Christopher¹,Pitman James¹,Easterbrook Linda¹,Richards Kevin S.¹,Burton Jane¹,Bewley Kevin¹^ORCID,Bruce Christine¹,Hiscox Julian A.²³,Carroll Miles W.¹⁴,Funnell Simon G. P.¹^ORCID

Affiliation:

1. UK Health Security Agency, Porton Down, Salisbury, United Kingdom

2. Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom

3. A*STAR Infectious Diseases Laboratories (A*STAR ID Labs), Agency for Science, Technology and Research (A*STAR), Singapore

4. Nuffield Department of Medicine, Oxford University, Oxford, United Kingdom

Abstract

Recent reemergence of Ebola in Guinea that caused over 28,000 cases between 2013 and 2016 has been linked to the original virus from that region. It appears the virus has remained in the region for at least 5 years and is likely to have been maintained in humans.

Funder

HHS | Biomedical Advanced Research and Development Authority

HHS | U.S. Food and Drug Administration

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00833-21

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5. Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus

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