Maternal Anti- Toxoplasma Treatment during Pregnancy Is Associated with Reduced Sensitivity of Diagnostic Tests for Congenital Infection in the Neonate

Author:

Guegan Hélène1,Stajner Tijana2,Bobic Branko2,Press Cindy3,Olariu Rares T.34,Olson Kjerstie3,Srbljanovic Jelena2,Montoya Jose G.3,Djurković-Djaković Olgica2,Robert-Gangneux Florence1ORCID

Affiliation:

1. Université de Rennes, CHU Rennes, Inserm, EHESP, Irset-UMR_S 1085, Rennes, France

2. National Reference Laboratory for Toxoplasmosis, Institute for Medical Research, University of Belgrade, Belgrade, Serbia

3. Dr. Jack S. Remington Laboratory for Specialty Diagnostics, Palo Alto, California, USA

4. Victor Babes University of Medicine and Pharmacy, Timisoara, Romania

Abstract

Neonatal diagnosis of congenital toxoplasmosis is based on a combination of serological and molecular tests. Maternal screening and treatment differ according to national policies and may impact the sensitivity of diagnostic methods in infants at birth.

Funder

Campus France

Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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