Unusual Relationship between Iron Deprivation and Organophosphate Hydrolase Expression

Author:

Nandavaram Aparna1,Nandakumar Anirudh23ORCID,Kashif G. M.1,Sagar Annapoorni Lakshman1,Shailaja G.1,Ramesh Arati2,Siddavattam Dayananda14

Affiliation:

1. Department of Animal Biology, School of Life Sciences, University of Hyderabad, Hyderabad, India

2. National Centre for Biological Sciences, Tata Institute of Fundamental Research, GKVK Campus, Bengaluru, India

3. The University of Trans-Disciplinary Health Sciences & Technology (TDU), Bengaluru, Karnataka, India

4. Department of Biochemistry, School of Sciences, GITAM University, Visakhapatnam, India

Abstract

Sphingobium fuliginis , a soil-dwelling microbe isolated from agricultural soils, was shown to degrade a variety of insecticides and pesticides. These synthetic chemicals function as potent neurotoxins, and they belong to a class of chemicals termed organophosphates. S. fuliginis codes for OPH, an enzyme that has been shown to be involved in the metabolism of several organophosphates and their derivatives.

Funder

DST | Science and Engineering Research Board

Department of Atomic Energy, Government of India

Department of Biotechnology, Ministry of Science and Technology, India

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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