Toxic Shock Syndrome Toxin 1-Producing Methicillin-Resistant Staphylococcus aureus of Clonal Complex 5, the New York/Japan Epidemic Clone, Causing a High Early-Mortality Rate in Patients with Bloodstream Infections

Author:

Kim Dokyun1,Hong Jun Sung1,Yoon Eun-Jeong1,Lee Hyukmin1,Kim Young Ah2,Shin Kyeong Seob3,Shin Jeong Hwan45,Uh Young6,Shin Jong Hee7,Park Yoon Soo8,Jeong Seok Hoon1

Affiliation:

1. Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, South Korea

2. Department of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang, South Korea

3. Department of Laboratory Medicine, Chungbuk National University College of Medicine, Cheongju, South Korea

4. Department of Laboratory Medicine, Inje University College of Medicine, Busan, South Korea

5. Paik Institute for Clinical Research, Inje University College of Medicine, Busan, South Korea

6. Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju, South Korea

7. Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, South Korea

8. Division of Infectious Diseases, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, South Korea

Abstract

This study was performed to evaluate the clinical impacts of putative risk factors in patients with Staphylococcus aureus bloodstream infections (BSIs) through a prospective, multicenter, observational study. All 567 patients with S. aureus BSIs that occurred during a 1-year period in six general hospitals were included in this study. Host- and pathogen-related variables were investigated to determine risk factors for the early mortality of patients with S. aureus BSIs.

Funder

MOHW | Korea Centers for Disease Control and Prevention

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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