Analysis of the Prevalence of Binding and Neutralizing Antibodies against 39 Human Adenovirus Types in Student Cohorts Reveals Low-Prevalence Types and a Decline in Binding Antibody Levels during the SARS-CoV-2 Pandemic-Reference-Cited by-同舟云学术

Analysis of the Prevalence of Binding and Neutralizing Antibodies against 39 Human Adenovirus Types in Student Cohorts Reveals Low-Prevalence Types and a Decline in Binding Antibody Levels during the SARS-CoV-2 Pandemic

Published:2022-11-23 Issue:22 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Wang Xiaoyan¹,Kerkmann Leonie¹,Hetzel Mario¹,Windmann Sonja¹,Trilling Mirko¹^ORCID,Zhang Wenli²,Ehrhardt Anja²,Bayer Wibke¹^ORCID

Affiliation:

1. Institute for Virology, University Hospital Essen, University Duisburg-Essen, Essen, Germany

2. Virology and Microbiology, Witten/Herdecke University, Witten, Germany

Abstract

Vectors based on human adenoviruses (HAdVs) are important for the development of novel immunizations, oncolytic therapies, and gene therapies. The use of HAdV-based vaccines against Ebola virus, the rapid adaptation of the vector technology for vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and their very good efficacy have shown the great potential of HAdV-based vaccines.

Funder

China Scholarship Council

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01133-22

Reference45 articles.

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2. The A.P.C. Viruses

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5. Adenovirus: Epidemiology, Global Spread of Novel Serotypes, and Advances in Treatment and Prevention

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