Affiliation:
1. Institute of Medical Microbiology, University of Zurich, 8028 Zurich, Switzerland
Abstract
In strain HK187 (
Streptococcus faecalis
subsp.
liquefaciens
) four plasmids were isolated. The molecular weights, as analyzed in neutral sucrose gradients and by electron microscopy, were found to be about 36 × 10
6
, 31 × 10
6
, 26 × 10
6
, and 4 × 10
6
. Plasmid 3, also designated pFK14, with a molecular weight of 26 × 10
6
, was found to be responsible for resistance to chloramphenicol and erythromycin and also for high-level resistance to streptomycin and lincomycin. In mixed cultures these four resistances could be transferred with high frequency to a plasmid-free recipient,
S. faecalis
strain JH2-2.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
31 articles.
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