Maternal Emulsifier P80 Intake Induces Gut Dysbiosis in Offspring and Increases Their Susceptibility to Colitis in Adulthood-Reference-Cited by-同舟云学术

Maternal Emulsifier P80 Intake Induces Gut Dysbiosis in Offspring and Increases Their Susceptibility to Colitis in Adulthood

Published:2021-04-27 Issue:2 Volume:6 Page:
ISSN:2379-5077
Container-title:mSystems
language:en
Short-container-title:mSystems

Author:

Jin Ge¹²,Tang Qiang¹²,Ma Jiaheng³,Liu Xiang¹²,Zhou Bingqian¹²,Sun Yue¹²,Pang Xiaoqi¹²,Guo Zixuan¹²,Xie Runxiang¹²,Liu Tianyu¹²,Wang Bangmao¹²,Cao Hailong¹²

Affiliation:

1. Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China

2. Tianjin Institute of Digestive Diseases, Tianjin Key Laboratory of Digestive Diseases, Tianjin, China

3. Department of Gastroenterology and Hepatology, Tianjin Union Medical Center, Tianjin, China

Abstract

The main findings of this research showed that maternal P80 intake could disrupt the intestinal barrier, induce gut dysbiosis, and promote colitis susceptibility in adulthood. This study will enhance understanding of the prevention of IBD.

Funder

Key Project of Science and Technology Pillar Program of Tianjin

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modelling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSystems.01337-20

Reference80 articles.

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5. Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

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