Periodically Disturbing the Spatial Structure of Biofilms Can Affect the Production of an Essential Virulence Factor in Pseudomonas aeruginosa-Reference-Cited by-同舟云学术

Periodically Disturbing the Spatial Structure of Biofilms Can Affect the Production of an Essential Virulence Factor in Pseudomonas aeruginosa

Published:2021-10-26 Issue:5 Volume:6 Page:
ISSN:2379-5077
Container-title:mSystems
language:en
Short-container-title:mSystems

Author:

Quinn Rebecca J.¹,Barraza Ivana¹,García-Diéguez Laura¹,Pajon Camryn¹,Krausfeldt Lauren E.¹^ORCID,Ibrahim Kerollos¹,Enzinna Laura A.¹,Thorn Morgan E.¹,Eldakar Omar Tonsi¹,Craddock Travis J. A.²³⁴⁵,Smith Robert P.¹^ORCID

Affiliation:

1. Department of Biological Sciences, Halmos College of Arts and Science, Nova Southeastern University, Fort Lauderdale, Florida, USA

2. Clinical Systems Biology Group, Institute for Neuro-Immune Medicine, Nova Southeastern University, Fort Lauderdale, Florida, USA

3. Department of Psychology and Neuroscience, College of Psychology, Nova Southeastern University, Fort Lauderdale, Florida, USA

4. Department of Computer Science, College of Engineering and Computing, Nova Southeastern University, Fort Lauderdale, Florida, USA

5. Department of Clinical Immunology, College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, Florida, USA

Abstract

Virulence factors are required to cause infections. Previous work has shown that the spatial organization of a population, such as a biofilm, can increase the production of some virulence factors, including pyoverdine, which is produced by Pseudomonas aeruginosa .

Funder

DOD | United States Army | RDECOM | ARO | Life Sciences Division, Army Research Office

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modelling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSystems.00961-21

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