The Adenoids but Not the Palatine Tonsils Serve as a Reservoir for Bacteria Associated with Secretory Otitis Media in Small Children

Author:

Fagö-Olsen Helena1,Dines Laura Marie1,Sørensen Christian Hjort1,Jensen Anders2

Affiliation:

1. Department of Otolaryngology and audiology, Copenhagen University Hospital Rigshospitalet/Gentofte, Copenhagen, Denmark

2. Department of Biomedicine, Faculty of Health Sciences, Aarhus University, Aarhus, Denmark

Abstract

Our findings that the microbiome differs between crypts of the adenoids and crypts of the palatine tonsils, including the relative abundances of potential pathogens such as Haemophilus influenzae , Streptococcus pneumoniae , and Moraxella catarrhalis , may be the stepping stone for further investigation of individual microbiomes in a longitudinal design that includes recording of the fluctuating health status of the child. Such studies may have the potential to lead to new preventive measurements such as implantation of protective nonpathogens at the nasopharynx as an alternative to adenoidectomy.

Funder

Dr. Jacob Madsen og Hustru Olga Madsen Fonden

Hans Skouby og hustru Emma Skouby Fond

Carl og Ellen Hertz legat

Alfred Helstad og Eli Møller legat

Rosalie Petersens Fond

Oda og Hans Svenningsens Fond

Oticon Fonden

Frimodt-Heineke Fonden

Velux Fonden

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modelling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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