Species-Specific Endotoxin Stimulus Determines Toll-Like Receptor 4- and Caspase 11-Mediated Pathway Activation Characteristics-Reference-Cited by-同舟云学术

Species-Specific Endotoxin Stimulus Determines Toll-Like Receptor 4- and Caspase 11-Mediated Pathway Activation Characteristics

Published:2021-08-31 Issue:4 Volume:6 Page:
ISSN:2379-5077
Container-title:mSystems
language:en
Short-container-title:mSystems

Author:

Ernst Orna¹,Khan Mohd M.²³,Oyler Benjamin L.³,Yoon Sung Hwan²,Sun Jing¹,Lin Fang-Yu⁴,Manes Nathan P.²^ORCID,MacKerell Alexander D.⁴,Fraser Iain D. C.¹,Ernst Robert K.⁵^ORCID,Goodlett David R.⁵,Nita-Lazar Aleksandra²^ORCID

Affiliation:

1. Signaling Systems Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

2. Functional Cellular Networks Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

3. School of Medicine, University of Maryland, Baltimore, Maryland, USA

4. Computer-Aided Drug Design Center, Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland, USA

5. Department of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, Maryland, USA

Abstract

Macrophages and monocytes are innate immune cells playing an important role in orchestrating the initial innate immune response to bacterial infection and the tissue damage. This response is facilitated by specific receptors on the cell surface and intracellularly.

Funder

International Research Agenda's Program for the Foundation of Polish Science

American Association of Pharmaceutical Scientists

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

Genome Canada

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSystems.00306-21

Reference79 articles.

1. Control of adaptive immunity by the innate immune system

2. Innate Immune Recognition

3. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

4. Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

5. Innate Immune Pattern Recognition: A Cell Biological Perspective

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. TLR signaling pathway and the effects of main immune cells and epigenetics factors on the diagnosis and treatment of infertility and sterility;Heliyon;2024-08

2. Enhancing SILCS-MC via GPU Acceleration and Ligand Conformational Optimization with Genetic and Parallel Tempering Algorithms;The Journal of Physical Chemistry B;2024-07-20

3. Novel microbiota Mesosutterella faecium sp. nov. has a protective effect against inflammatory bowel disease;Frontiers in Microbiology;2024-04-02

4. Lipopolysaccharide Regulates the Macrophage RNA-Binding Proteome;Journal of Proteome Research;2024-03-25

5. Myristoylated, alanine-rich C-kinase substrate (MARCKS) regulates toll-like receptor 4 signaling in macrophages;Scientific Reports;2023-11-10