Characterization of the Pig Gut Microbiome and Antibiotic Resistome in Industrialized Feedlots in China

Author:

Wang Chunlai1,Li Peng2,Yan Qiulong3,Chen Liping1,Li Tiantian1,Zhang Wanjiang1,Li He1,Chen Changming3,Han Xiuyan3,Zhang Siyi3,Xu Miao3,Li Bo3,Zhang Xiaoxuan4,Ni Hongbo4,Ma Yufang3,Dong Bo2,Li Shenghui2,Liu Siguo1

Affiliation:

1. State Key Laboratory of Veterinary Biotechnology, Division of Bacterial Diseases, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China

2. Shenzhen Puensum Genetech Institute, Shenzhen, China

3. Department of Microbiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China

4. College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, China

Abstract

The gut microbiota is believed to be closely related to many important physical functions in the host. Comprehensive data on mammalian gut metagenomes has facilitated research on host-microbiome interaction mechanisms, but less is known about pig gut microbiome, especially the gut microbiome in industrialized feedlot pigs, compared with human microbiome. On the other hand, pig production, as an important source of food, is believed to exacerbate the antibiotic resistance in humans due to the abuse of antibiotics in pig production in various parts of the world. This study delineates an intricate picture of swine gut microbiome and antibiotic resistome in industrialized feedlots and may provide insight for the pig producing industry.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Natural Science Foundation of Heilongjiang Province of China

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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