A Genome-Scale Atlas Reveals Complex Interplay of Transcription and Translation in an Archaeon-Reference-Cited by-同舟云学术

A Genome-Scale Atlas Reveals Complex Interplay of Transcription and Translation in an Archaeon

Published:2023-04-27 Issue:2 Volume:8 Page:
ISSN:2379-5077
Container-title:mSystems
language:en
Short-container-title:mSystems

Author:

Lorenzetti Alan P. R.¹²^ORCID,Kusebauch Ulrike²^ORCID,Zaramela Lívia S.¹^ORCID,Wu Wei-Ju²,de Almeida João P. P.¹^ORCID,Turkarslan Serdar²^ORCID,L. G. de Lomana Adrián²^ORCID,Gomes-Filho José V.¹^ORCID,Vêncio Ricardo Z. N.³^ORCID,Moritz Robert L.²^ORCID,Koide Tie¹^ORCID,Baliga Nitin S.²⁴⁵⁶⁷^ORCID

Affiliation:

1. Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil

2. Institute for Systems Biology, Seattle, Washington, USA

3. Department of Computation and Mathematics, Faculty of Philosophy, Sciences and Letters at Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil

4. Department of Biology, University of Washington, Seattle, Washington, USA

5. Department of Microbiology, University of Washington, Seattle, Washington, USA

6. Molecular and Cellular Biology Program, University of Washington, Seattle, Washington, USA

7. Lawrence Berkeley National Lab, Berkeley, California, USA

Abstract

While the transcriptional regulation landscape of archaea has been extensively investigated, we currently have limited knowledge about post-transcriptional regulation and its driving mechanisms in this domain of life. In this study, we collected and integrated omics data from multiple sources and technologies to infer post-transcriptionally regulated genes and the putative mechanisms modulating their expression at the protein level in Halobacterium salinarum NRC-1.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado de São Paulo

HHS | NIH | NIH Office of the Director

HHS | NIH | National Institute of General Medical Sciences

National Science Foundation

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/msystems.00816-22

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