The Sixth Element: a 102-kb RepABC Plasmid of Xenologous Origin Modulates Chromosomal Gene Expression in Dinoroseobacter shibae

Author:

Koppenhöfer Sonja1ORCID,Tomasch Jürgen2ORCID,Ringel Victoria3,Birmes Lukas3,Brinkmann Henner3,Spröer Cathrin3,Jarek Michael4,Wang Hui5,Pradella Silke3,Wagner-Döbler Irene5ORCID,Petersen Jörn35ORCID

Affiliation:

1. Department of Biology, Memorial University of Newfoundland, St. John’s, Newfoundland, Canada

2. Laboratory of Anoxygenic Phototrophs, Institute of Microbiology of the Czech Academy of Science—Centre Algatech, Třeboň, Czech Republic

3. Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH, Braunschweig, Germany

4. Group Genome Analytics, Helmholtz Centre for Infection Research, Braunschweig, Germany

5. Institute of Microbiology, TU Braunschweig, Braunschweig, Germany

Abstract

Plasmids are small DNA molecules that replicate independently of the bacterial chromosome. The common view of the role of plasmids is dominated by the accumulation of resistance genes, which is responsible for the antibiotic crisis in health care and livestock breeding.

Funder

Deutsche Forschungsgemeinschaft

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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