Ecological Adaptation and Succession of Human Fecal Microbial Communities in an Automated In Vitro Fermentation System

Author:

Gnanasekaran Thiyagarajan1,Assis Geraldo Juliana1,Ahrenkiel David Wilczek1,Alvarez-Silva Camila1,Saenz Carmen1,Khan Adnan1,Hanteer Obaida1,Gunalan Vithiagaran1,Trost Kajetan1,Moritz Thomas1,Arumugam Manimozhiyan1ORCID

Affiliation:

1. Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Abstract

In vitro fermentors that can host complex gut microbial communities are promising tools to investigate the dynamics of human gut microbiota. In this work, using an automated in vitro gut fermentor consisting of different colon compartments, we investigated the adaptation dynamics of two different human fecal microbial communities over 22 and 31 days.

Funder

Novo Nordisk Fonden

Teknologi og Produktion, Det Frie Forskningsråd

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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