BiG-MAP: an Automated Pipeline To Profile Metabolic Gene Cluster Abundance and Expression in Microbiomes-Reference-Cited by-同舟云学术

BiG-MAP: an Automated Pipeline To Profile Metabolic Gene Cluster Abundance and Expression in Microbiomes

Published:2021-10-26 Issue:5 Volume:6 Page:
ISSN:2379-5077
Container-title:mSystems
language:en
Short-container-title:mSystems

Author:

Pascal Andreu Victória¹^ORCID,Augustijn Hannah E.¹^ORCID,van den Berg Koen¹,van der Hooft Justin J. J.¹^ORCID,Fischbach Michael A.²³⁴^ORCID,Medema Marnix H.¹^ORCID

Affiliation:

1. Bioinformatics Group, Wageningen University, Wageningen, the Netherlands

2. Department of Bioengineering, Stanford University, Stanford, California, USA

3. Department of Microbiology and Immunology, Stanford University, Stanford, California, USA

4. ChEM-H, Stanford University, Stanford, California, USA

Abstract

Microbes play an increasingly recognized role in determining host-associated phenotypes by producing small molecules that interact with other microorganisms or host cells. The production of these molecules is often encoded in syntenic genomic regions, also known as gene clusters.

Funder

Chan Zuckerberg Initiative

DOD | Defense Advanced Research Projects Agency

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modelling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSystems.00937-21

Reference57 articles.

1. Small molecules from the human microbiota

2. The rhizosphere microbiome and plant health

3. Bacterial competition: surviving and thriving in the microbial jungle

4. Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease

5. Ethanolamine utilization in bacterial pathogens: roles and regulation

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Interplay Between the Gut Microbiome and Typhoid Fever: Insights from Endemic Countries and a Controlled Human Infection Model;2024-09-03

2. Unlocking the biosynthetic potential and taxonomy of the Antarctic microbiome along temporal and spatial gradients;Microbiology Spectrum;2024-06-04

3. A meta-analysis of the gut microbiome in inflammatory bowel disease patients identifies disease-associated small molecules;2024-02-08

4. Identification of peptides from honeybee gut symbionts as potential antimicrobial agents against Melissococcus plutonius;Nature Communications;2023-11-24

5. A widely distributed gene cluster compensates for uricase loss in hominids;Cell;2023-08