Increased Proportion of Fiber-Degrading Microbes and Enhanced Cecum Development Jointly Promote Host To Digest Appropriate High-Fiber Diets

Author:

Pu Guang1,Hou Liming12,Du Taoran1,Zhou Wuduo1,Liu Chenxi1,Niu Peipei2,Wu Chengwu2,Bao Wenbin3,Huang Ruihua142,Li Pinghua142

Affiliation:

1. Key Laboratory of Pig Genetic Resources Evaluation and Utilization (Nanjing), Ministry of Agriculture and Rural Affairs, Institute of Swine Science, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China

2. Laboratory of Intestinal Microbiology, Huaian Academy, Nanjing Agricultural University, Nanjing, China

3. Key Laboratory for Animal Genetics, Breeding, Reproduction and Molecular Design, College of Animal Science and Technology, Yangzhou University, Yangzhou, China

4. Industrial Technology System Integration Innovation Center of Jiangsu Modern Agriculture (Pig), Nanjing, China

Abstract

Although studies about the effects of dietary fiber on fiber digestion and intestinal microbiota of pigs were widely in progress, few studies have been conducted on the dynamic response of intestinal microbiota to dietary fiber levels, and the characteristics of intestinal microbiota and intestinal epithelial development adapted to high-fiber diet s were still unclear. Appropriate high fiber promoted the thickness of large intestine wall, increased the density of cecal goblet cells, and promoted the renewal of cecal epithelial cells.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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