Systematic Analysis of Metabolic Bottlenecks in the Methylerythritol 4-Phosphate (MEP) Pathway of Zymomonas mobilis-Reference-Cited by-同舟云学术

Systematic Analysis of Metabolic Bottlenecks in the Methylerythritol 4-Phosphate (MEP) Pathway of Zymomonas mobilis

Published:2023-04-27 Issue:2 Volume:8 Page:
ISSN:2379-5077
Container-title:mSystems
language:en
Short-container-title:mSystems

Author:

Khana Daven B.¹²³,Tatli Mehmet¹²,Rivera Vazquez Julio¹²³,Weraduwage Sarathi M.⁴,Stern Noah¹²,Hebert Alexander S.¹⁵,Angelica Trujillo Edna¹⁶,Stevenson David M.¹²,Coon Joshua J.¹⁷⁶⁸,Sharky Thomas D.⁴,Amador-Noguez Daniel¹²^ORCID

Affiliation:

1. DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, Wisconsin, USA

2. Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA

3. Microbiology Doctoral Training Program, University of Wisconsin-Madison, Wisconsin, USA

4. MSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, Michigan, USA

5. Genome Center of Wisconsin, Madison, Wisconsin, USA

6. Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA

7. Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA

8. Morgridge Institute for Research, Madison, Wisconsin, USA

Abstract

Engineered microorganisms have the potential to convert renewable substrates into biofuels and valuable bioproducts, which offers an environmentally sustainable alternative to fossil-fuel-derived products. Isoprenoids are a diverse class of biologically derived compounds that have commercial applications as various commodity chemicals, including biofuels and biofuel precursor molecules.

Funder

U.S. Department of Energy

U.S. National Institutes of Health

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/msystems.00092-23

Reference84 articles.

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