Exploring Proteomes of Robust Yarrowia lipolytica Isolates Cultivated in Biomass Hydrolysate Reveals Key Processes Impacting Mixed Sugar Utilization, Lipid Accumulation, and Degradation

Author:

Walker Caleb1,Dien Bruce2,Giannone Richard J.3,Slininger Patricia2,Thompson Stephanie R.2,Trinh Cong T.1ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering, University of Tennessee, Tennessee, USA

2. Bioenergy Research Unit, The National Center for Agricultural Utilization Research, USDA-ARS, Peoria, Illinois, USA

3. Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA

Abstract

Yarrowia lipolytica is an important industrial oleaginous yeast due to its robust phenotypes for effective conversion of inhibitory lignocellulosic biomass hydrolysates into neutral lipids. While lipid accumulation has been well characterized in this organism, its interconnected lipid degradation phenotype is poorly understood during fermentation of biomass hydrolysates.

Funder

U.S. Department of Energy

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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