Phenotypic and Genomic Diversification in Complex Carbohydrate-Degrading Human Gut Bacteria

Author:

Pudlo Nicholas A.1,Urs Karthik1,Crawford Ryan2,Pirani Ali1,Atherly Todd34,Jimenez Roberto5,Terrapon Nicolas67,Henrissat Bernard678,Peterson Daniel59,Ziemer Cherie34,Snitkin Evan1ORCID,Martens Eric C.1ORCID

Affiliation:

1. Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA

2. Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, Michigan, USA

3. Iowa State University, Department of Animal Science, Ames, Iowa, USA

4. United States Department of Agriculture Agricultural Research Station, Ames, Iowa, USA

5. University of Nebraska, Department of Food Sciences, Lincoln, Nebraska, USA

6. Aix Marseille Univ, CNRS, UMR7257 AFMB, Marseille, France

7. INRAE, USC1408 AFMB, Marseille, France

8. Department of Biological Sciences, King Abdulaziz University, Jeddah, Saudi Arabia

9. Johns Hopkins University, Department of Pathology, Baltimore, Maryland, USA

Abstract

Nonharmful bacteria are the primary microbial symbionts that inhabit the human gastrointestinal tract. These bacteria play many beneficial roles and in some cases can modify disease states, making it important to understand which nutrients sustain specific lineages.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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