Quantitative Proteomics Reveals Metabolic Reprogramming in Host Cells Induced by Trophozoites and Intermediate Subunit of Gal/GalNAc Lectins from Entamoeba histolytica-Reference-Cited by-同舟云学术

Quantitative Proteomics Reveals Metabolic Reprogramming in Host Cells Induced by Trophozoites and Intermediate Subunit of Gal/GalNAc Lectins from Entamoeba histolytica

Published:2022-04-26 Issue:2 Volume:7 Page:
ISSN:2379-5077
Container-title:mSystems
language:en
Short-container-title:mSystems

Author:

Zhao Yanqing¹,Li Xia¹²,Zhou Ruixue¹,Zhang Lei³,Chen Lijun¹,Tachibana Hiroshi⁴^ORCID,Feng Meng¹,Cheng Xunjia¹^ORCID

Affiliation:

1. Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Fudan University, Shanghai, China

2. Affiliated Hospital of Guizhou Medical University, Guiyang, China

3. Institutes of Biomedical Sciences, Fudan University, Shanghai, China

4. Department of Infectious Diseases, Tokai University School of Medicine, Isehara, Kanagawa, Japan

Abstract

Metabolic reprogramming is considered a hallmark of some infectious diseases. However, in amoebiasis, a neglected tropical disease caused by protozoan parasite E. histolytica , metabolic changes in host cells have yet to be proven.

Funder

MOST | National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/msystems.01353-21

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4. Entamoeba

5. The Bittersweet Interface of Parasite and Host: Lectin-Carbohydrate Interactions During Human Invasion by the Parasite Entamoeba histolytica