Comparative Molecular and Immunoregulatory Analysis of Extracellular Vesicles from Candida albicans and Candida auris

Author:

Zamith-Miranda Daniel12ORCID,Heyman Heino M.3,Couvillion Sneha P.3,Cordero Radames J. B.4ORCID,Rodrigues Marcio L.56ORCID,Nimrichter Leonardo6ORCID,Casadevall Arturo4ORCID,Amatuzzi Rafaela F.5,Alves Lysangela R.5ORCID,Nakayasu Ernesto S.3ORCID,Nosanchuk Joshua D.12

Affiliation:

1. Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA

2. Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA

3. Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USA

4. Harry Feinstone Molecular Microbiology and Immunology Department, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

5. Carlos Chagas Institute, Fundação Oswaldo Cruz (Fiocruz), Curitiba, Brazil

6. Microbiology Institute Paulo de Góes (IMPG), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

Abstract

Candida auris is a recently described multidrug-resistant pathogenic fungus that is responsible for outbreaks across the globe, particularly in the context of nosocomial infections. Its virulence factors and pathogenesis are poorly understood.

Funder

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro

Fundação Oswaldo Cruz

HHS | National Institutes of Health

MCTI | Conselho Nacional de Desenvolvimento Científico e Tecnológico

Ministério da Saúde

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modelling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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