Genomic Diversity and Antimicrobial Resistance of Haemophilus Colonizing the Airways of Young Children with Cystic Fibrosis

Author:

Watts Stephen C.12,Judd Louise M.2,Carzino Rosemary3,Ranganathan Sarath34,Holt Kathryn E.125ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Melbourne, Victoria, Australia

2. Department of Infectious Diseases, Central Clinical School, Monash University, Melbourne, Victoria, Australia

3. Infection and Immunity, Murdoch Children’s Research Institute, Melbourne, Victoria, Australia

4. Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia

5. London School of Hygiene & Tropical Medicine, London, United Kingdom

Abstract

Cystic fibrosis (CF) lung disease begins during infancy, and acute respiratory infections increase the risk of early disease development and progression. Microbes involved in advanced stages of CF are well characterized, but less is known about early respiratory colonizers.

Funder

Bill and Melinda Gates Foundation

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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