Emergence and Expansion of a Carbapenem-Resistant Pseudomonas aeruginosa Clone Are Associated with Plasmid-Borne bla KPC-2 and Virulence-Related Genes-Reference-Cited by-同舟云学术

Emergence and Expansion of a Carbapenem-Resistant Pseudomonas aeruginosa Clone Are Associated with Plasmid-Borne bla KPC-2 and Virulence-Related Genes

Published:2021-05-18 Issue: Volume: Page:
ISSN:2379-5077
Container-title:mSystems
language:en
Short-container-title:mSystems

Author:

Hu Yanyan¹,Liu Congcong¹,Wang Qi¹,Zeng Yu¹,Sun Qiaoling¹,Shu Linbin¹,Lu Jiayue¹,Cai Jiacang¹,Wang Shaolin²^ORCID,Zhang Rong¹,Wu Zuowei³^ORCID

Affiliation:

1. Department of Clinical Laboratory, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China

2. College of Veterinary Medicine, China Agricultural University, Beijing, China

3. Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA

Abstract

Health care-associated infections, also known as nosocomial infections, are the most frequent adverse events in health care delivery worldwide, causing high rates of morbidity and mortality and high health care costs. Pseudomonas aeruginosa is one of the leading bacterial species causing health care-associated infections. Carbapenems are the most effective antimicrobial agents for the treatment of its severe infections.

Funder

the natural science foundation of Zhejiang province

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modelling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSystems.00154-21

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